Malignant mesothelioma in the Italian region Emilia Romagna: incidence and asbestos exposure update to 2020
Malignant mesothelioma (MM) is a rare disease of great interest to the scientific community and to public health due to its high lethality and to its association with asbestos exposure.
The aim of this study, is to describe the incidence of MM in the period 1996-2020 with the related exposure to asbestos.
The data was collected by the Regional Mesothelioma Registry (ReM) which represents one of the 21 CORs (Regional Operational Centers) in Italy.
The study includes all cases of MM with a certain or a probable diagnosis (with microscopic confirmation) and possible cases (without microscopic confirmation).
For each case, information on sex, date of birth, tumor site, morphology, date of diagnosis, follow-up and province of residence was retrieved. We collected information on previous occupational and non-occupational exposure to asbestos, by type of sector and activity.
The exposure information is collected through the ReNaM (National Mesothelioma Registry) analytical questionnaire, administered to the patient or his closest relatives. The data collection is conducted by a regional survey network.
Were registered, between 1996 and 2020, 3013 cases of MM classified as certain (85.2%), probable
(5.4%) and possible cases (9.4%). The greatest number of cases are recorded for the pleura (2,763)
and for the peritoneum (224) in the province of Bologna, Reggio Emilia, Parma and Modena. The most affected age groups are 65-74 and 75 +. Concerning exposure, 70.3% was defined professional, 6.0% familiar, 2.3% environmental and 1.3% extra professional.
As regards the provinces of residence, Bologna holds the primacy for cases of professional and environmental exposure, Reggio Emilia for familiar and Parma for extra-professional exposure. Most of the exposure to asbestos is recorded in the construction and in the railway sector, mainly in males.